FOLLICULAR FLUID-DERIVED EXOSOMAL MIR-143-3P/MIR-155-5P REGULATE FOLLICULAR DYSPLASIA BY MODULATING GLYCOLYSIS IN GRANULOSA CELLS IN POLYCYSTIC OVARY SYNDROME

Abstract Objective Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia.An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS.Follicular fluid (FF) exosomal microRNAs (miRNAs) have been proven to regulate the function of GCs.In this study, exosomes extrac

(1) Current literature on ethnic minorities, comorbidities, and COVID-19 tends to investigate these factors separately, leaving gaps in our understanding about their interactions.Our review seeks to identify a relationship between ethnicity, comorbidities, and severe COVID-19 outcomes (ICU admission and mortality).We hope to enhance our understandi

Northwestern Bantu 730 sunken lake road is the most linguistically diverse area of the Bantu-speaking world.Several unusual grammatical gender systems are reported for this area, but there has been a lack of comprehensive comparative studies.This article is a typological investigation of northwestern Bantu gender systems based on a sample of 179 la

Background: Food allergy prevalence has continued to rise over the past decade.While studies have reported threshold doses for multiple foods, large-scale multi-food allergen studies are lacking.Our goal was to identify threshold dose distributions and predictors of severe reactions during blinded oral food challenges (OFCs) in multi-food allergic